This site was built with web standards. You are currently viewing the unformatted version of the website. Please update your browser in order to view the site.
Internet Explorer 5 or greater
Netscape 7
Mozilla
Opera 6 or greater
Within the chromosome, DNA is packaged into chromatin. Chromatin consists of DNA, structural histone proteins, and nonhistone proteins.7 Histones are responsible for maintaining the chromatin's shape and structure.7,14,15 The chromatin structure is controlled by a variety of histone modifications, including methylation, phosphorylation, and acetylation, that occur at the aminoterminal tails of the histones. Acetylation of the histone tails is now generally acknowledged to play a key role in the regulation of gene expression.7,16
