HDAC Quiz

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HDAC Hypothesized Mechanism of Action Quiz

How much do you know about HDAC? Please take this short quiz to find out:

1.Epigenetics refers to modifications that modulate when and the levels at which genes are expressed or repressed without changes in the DNA sequence.
A. True
B. False
2.Which of the following is an epigenetic process?
A. Mutation
B. Deletion
C. Deacetylation
D. Translocation
3.Within the chromosome, DNA is packaged into histones.
A. True
B. False
4.Histone acetylation and deacetylation:
A. Cause chromatin remodeling
B. Alter the interaction of genes with transcriptional machinery
C. Regulate gene expression
D. All of the above
5.Overexpressed or sustained HDAC activity, occurring in some cancer cells, may prevent the transcription of proteins, such as tumor suppressor genes, such as p53, and cyclin-dependent kinase inhibitors, such as p21.
A. True
B. False

Clear

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